Endocrine Abstracts

Amiodarone, an iodine-containing antiarrhythmic drug frequently used in chronic heart failure (CHF) patients, is often the cause of primary hypothyroidism. It has not been well investigated, however, whether its use could lead to a poor prognosis in these patients by inducing and/or worsening thyroid function. The aim of this study was to evaluate the prognostic significance of hypothyroidism detection in CHF outpatients treated with amiodarone. Out of 355 patients affected by...

The aim of this study was to evaluate the prognostic role of subclinical hypothyroidism in patients with chronic heart failure (CHF). We evaluated 338 consecutive outpatients (260 male; age 64±13) with stable CHF (NYHA class 2.3±0.6) receiving conventional therapy (ACE inhibitors and/or ARBs 93%, Beta-blockers 88%, Digitalis 26%, Diuretics 85%, Spironolactone 54%, Amiodarone 32%). The patients underwent a physical examination, electrocardiography and echocardiography...